CCA News & Information Articles

Arsenic-induced micronuclei formation in Mammalian cells and its counteraction by tea 03-07-2005 The results showed that both green tea and black tea extracts have equal potential in modulating the arsenic-induced genotoxicity. This effect was perhaps induced by the constituent polyphenols present in green and black tea. In addition, the repair activity of the damaged cells was enhanced when treated with these tea extracts and their polyphenols. Thus, tea and its polyphenols may have a promising role in counteracting the devastating effects of arsenic. Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity. pub med Co-exposures to complex mixtures of arsenic and polycyclic aromatic hydrocarbons such as benzo[a]pyrene (BaP) are common in the environment. These two environmental pollutants are carcinogenic, but the nature of their molecular interactions in the induction of cancer is not well understood. ATM status confers sensitivity to arsenic cytotoxic effects ATM status confers sensitivity to arsenic cytotoxic effects